Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.
Study identifier: NCT04706234. Status: RECRUITING.
Eligibility
Criteria: Inclusion Criteria: * diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or * diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or * diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015) * Hoehn and Yahr Stage within the range of I-V or * diagnosis of motor neurone disease or * diagnosis of a neurodegenerative disease other than specified above AND underwent laryngopharyngeal assessment according to the systematic task protocol during FEES (Warnecke et al. 2019). Exclusion Criteria: \- Patients who do not sign the consent form
- Minimum age: 18 Years
Participating locations
- Department of Neurology and Department of ENT, Medical University Innsbruck, Innsbruck, Tyrol
- Department of Neurology, Medical University of Ulm, Ulm, Baden-Wurttemberg
- Movement Disorders Hospital - Kliniken Beelitz, Beelitz-Heilstätten, Brandenburg
- Department of Neurology, Medical School Hannover, Hanover, Lower Saxony
- Department of Neurology, University Hospital Münster, Münster, North Rhine-Westphalia
- Department of Neurology, University Hospital Carl Gustav Carus, Dresden, Saxony
- Department of Neueology Asklepios Klinik Stadtroda, Stadtroda, Thuringia
- Asklepios Fachklinikum Stadtroda, Stadtroda, Thuringia
- Asklepios Klinik Barmbek, Hamburg
- Department of Neurology Asklepios Klinik Barmbek, Hamburg
Study records are sourced from ClinicalTrials.gov. Confirm current eligibility, recruiting status, and locations in the official record.